2019 HEALTH SPAN HAWAII

SPEAKERS

Join us for exciting keynote presentations and numerous networking opportunities with experts, researchers, and up-and-coming leaders in the field of Regenerative Medicine.

ARNOLD CAPLAN, PHD

Case Western Reserve University
Director, Skeletal Research Center

Arnold Caplan, Ph.D is a national and international scholar focusing on experimentation in the area of musculoskeletal and skin development. He has published over 400 papers and manuscripts and has been supported by the NIH and other non-profit and for-profit agencies for his efforts in trying to understand the development, maturation, and aging of cartilage, bone, skin, and other mesenchymal tissues and his pioneering research on Mesenchymal Stem Cells.

WARREN SHERMAN, MD

Chief Medical Officer, Black Beret Life Sciences
Interventional Cardiologist, Okyanos

Dr. Warren Sherman, MD is a renowned interventional cardiologist with a long and established focus in cell-based therapies. As Chief Medical Officer and a treating physician at Okyanos, Dr. Sherman provides the highest level of care using stem cell therapies for patients with chronic heart failure and refractory angina. Dr. Sherman pioneered a technique for injecting stem cells into the heart and was the first to perform the procedure on a patient.

Al Zoubi

Stem Cell Scientist and a Cancer Immunologist
Founding President/CEO
Stem Cells of Arabia

Assistant Professor
Department of Hematology/Oncology
University of Illinois at Chicago

Dr. Al-Zoubi research interests focus on developing safe and effective methods for the utilization of purified populations of stem cells in treatment of chronic and devastating diseases. Iearned a bachelor’s degree in Medical Technology from Southwestern University, Philippines, a Master’s degree in Clinical Laboratory Sciences from Rosalind Franklin University, USA, and aPh.D. in Immunology from the College of Medicine, University of Illinois at Chicago, USA.

RICHARD ALLSOPP

Institute For Biogenesis Research

Uiversity of Hawaii. John A. Burns School of Medicine 

Dr. Allsopp’s major research focus is the cellular and molecular mechanisms of aging. In particular, he has long been interested in telomere-induced senescence, factors which regulate telomerase in stem cells, and on developing novel telomerase-based therapies to treat age-related diseases. Of note, Dr. Allsopp’s lab was the first to discover the essential role of Hif1 on telomerase expression in embryonic stem cells. He is also interested in studying age-dependent changes in stem cell populations in adult organisms, including humans. He has over 10 years experience in studying and isolating hematopoietic stem cells and 20 years experience in studying telomere & telomerase biology. Recently, he has shown that adipose derived stem cells are particularly useful in treating infarcts in a human-to-rodent model system.
Dr. Allsopp received his PhD from McMaster University, Hamilton Ontario Canada. Subsequently, he spent five years training in the prestigious stem cell lab of Dr. Irving Weissman at Stanford University, before joining the University of Hawaii as faculty in 2003.

MICHELE CARBONE

Director, Thoracic Oncology, University of Hawaiʻi Cancer Center
Full Member, Cancer Biology Program, University of Hawaiʻi Cancer Center

Dr. Michele Carbone, MD, PhD is Professor of Pathology and served as Director of the University of Hawai‘i Cancer Center, a NCI-designated cancer center from 2009-2014, after being Interim Director from 2008-2009. Dr. Carbone worked at the National Institutes of Health (NIH) from 1986 to 1994, at the University of Chicago and Loyola University Cancer Center of Chicago rfom 1994 until 2006, when he joined the University of Hawai‘i Mānoa.
Dr. Carbone discovered the mechanism of asbestos carcinogenesis and found that SV40, a virus that contaminated polio vaccine, synergizes with asbestos in causing mesothelioma. He studied an epidemic of mesothelioma in Cappadocia, Turkey, and demonstrated the existence of a genetic susceptibility factor. Following up on that research, Dr. Carbone studied US families with high incidence of mesothelioma and he discovered a new cancer syndrome that linked BAP1 germline mutations to the development of mesothelioma, uveal melanoma and other cancers. His discoveries of extensive erionite exposure in North Dakota, U.S., led to cancer preventive measures and social and community improvements. In parallel studies, Dr. Carbone, in collaboration with Dr. Haining Yang, studied the role of HMGB1-driven inflammation in the pathogenesis of mesothelioma.

STEFAN IRION

Vice President of Neuroscience

BlureRock Therapeutics

Stefan Irion, M.D., joined BlueRock bringing deep knowledge of cell therapies from his research experience in both academia and industry. Dr. Irion has been working on the development team for BlueRock’s lead cellular therapeutic candidate targeting Parkinson’s disease since 2013, when he served as program manager at Memorial Sloane Kettering. He transitioned to BlueRock in 2017, assuming management of the neurology program in house. Prior to Memorial Sloane Kettering, Dr. Irion worked as a senior scientist and project team leader at iPierian, a role in which he developed an induced pluripotent stem cell model of Alzheimer’s disease that led to the discovery of a novel anti-tau antibody. Bristol-Myers Squibb acquired iPierian in a $725M deal in 2014. Dr. Irion was previously a postdoctoral fellow at the University Health Network, specializing in cell biology and gene targeting, and at the Mount Sinai School of Medicine. He holds an M.D. from the University of Tübingen in Germany.

Betsy Myers

Leadership Expert, Founding Director, Center for Women & Business at Bentley University
Former Executive Director, Harvard’s Center for Public Leadership

Betsy Myers speaks about the importance of executive sponsorship programs to drive the advancement of women.Prior to joining the Clinton Administration, Myers spent six years building Myers Insurance & Financial Services based in Los Angeles. She specialized in the small business and the women’s market providing insurance and retirement planning.A Public Service Fellow at Harvard’s Kennedy School, Betsy graduated with a Masters in Public Administration, and then served as the School’s Director of Alumni Programs & External Relations before her role at the Center for Public Leadership.Betsy is currently speaking and leading workshops around the world on the changing nature of leadership. Her book, Take the Lead: Motivate, Inspire, and Bring Out the Best in Yourself and Everyone Around You, continues to be the basis of her work as her experience spans the corporate, political and higher education arena.

Mari Dezawa

Professor
Stem Cell Biology and Histology   
Tohoku University School of Medicine, Japan.

Mari Dezawa is graduated from Chiba University School of Medicine in 1989 andreceived her PhD degree in 1995 at the same institution. She moved to Yokohama City University as Assistant Professor of Dept Anatomy in 2000 where she started to work with mesenchymal stem cells (MSCs). After moving to Kyoto University Graduate School of Medicine as Associate Professor in 2003, she discovered methods to induce neurons and skeletal muscle cells from human MSCs. In 2008, she became Professor and Chair of Department of Stem Cell Biology and Histology, Tohoku University Graduate School of Medicine, where she discovered muse cells (PNAS, 2010, PNAS, 2011, Nat Protocol, 2013, JASN, 2017).

Paterlini-Brechot

Professor
Cell Biology and Oncology
Faculté de Médecine Necker-Enfants Malades, 
Université Paris Descartes and at INSERM in Paris.

Dr. Paterlini-Bréchot studied medicine at the University of Modena, where she specialized in haematology and oncology. After working as a cancer specialist in Bologna, she felt that the most concrete way of helping patients in the long term would be to focus on biomedical research. In 1988 she moved to Paris to train in molecular biology, completing her PhD in 1993 at University of Paris XI on the fundamental bases of oncogenesis. Today Paterlini-Bréchot is Professor of Cellular and Molecular Biology/Oncology at Paris Descartes University, a practitioner in the Paris public hospital system, team research leader at French public research organization INSERM, and scientific advisor to a company she also founded.

Camillo Ricordi

Stacy Joy Goodman Professor of Surgery
Distinguished Professor of Medicine
Professor of Biomedical Engineering, and Microbiology and Immunology
University of Miami (UM), Florida
Director of the Diabetes Research Institute (DRI) and the Cell Transplant Program

Dr. Ricordihas been serving as Responsible Head of the NIH-funded cGMP (current Good Manufacturing Practices) Human Cell Processing Facility (1993-present), for the manufacturing of advanced human cell and other biologic products, for research and clinical applications at the University of Miami, in the U.S. and worldwide. Dr. Ricordi has also served as Senior Associate Dean for Research (2003-2006) and chaired the Dean’s Research Cabinet (2006-2012) at the UM Miller School of Medicine.

Jan Nolta

Director
Stem Cell Program at UC Davis School of Medicine
Institute for Regenerative Cures

The UC Davis stem cell program has over 145 faculty members collaborating to work toward stem cell-related cures for a spectrum of diseases and injuries. The current research in Dr. Nolta’s laboratory is focused on developing therapies that will use mesenchymal stem cells (MSCs) to deliver factors for treating Huntington’s disease and other disorders and injuries. Her group focuses on “bench to the bedside” research, and she has been involved in numerous clinical trials of gene and cell therapy. She is scientific director of the new Good Manufacturing Practice clean room facility at UC Davis, where stem cells of different types are being isolated or expanded for clinical trials.

Joseph Purita

Director
Institute of Regenerative and Molecular Orthopedics (www.stemcellorthopedic.com)
Boca Raton, Florida.

Dr. Purita is a pioneer in the use of Stem Cells and Platelet Rich Plasma. He received a B.S. and MD degree from Georgetown Univ. Dr. Purita is board certified in Orthopedics by ABOS. He is a Fellow American College of Surgeons, Fellow American Academy Orthopedic Surgeons, and a Fellow American Academy of Pain Management. He has lectured and taught extensively throughout the world on the use of Stem Cells and Platelet Rich Plasma. He has helped countries develop Stem Cell policies.

Michael Edwards

Co-Founder US Authentic Trading Company.

Dr. Edwards brings to bear combined medical, business, and scientific expertise as CEO of US Authentic Trading Company. Dr. Edwards is an expert in complex brand and product introduction into the Chinese consumer market having successfully navigated international regulatory compliance issues across a broad spectrum from mobile technology to healthcare products.

Barbara Krutchkoff

Executive Director, Institute of Regenerative and Cellular Medicine
Co-Founder, Lester Smith Medical Research Institute
Founder, The Humanity Fund
CEO of A3Cell/consultancy
Professor Universite Paris Descartes.

Barbara Krutchkoff, PhDis a consultant for physicians and biomedical start-up companies in regenerative and cellular medicine. She is Executive Director of the 501c3Institute of Regenerative and Cellular Medicine, and Co-Chair of the IRB, which provides support for translational research and validation of regenerative therapies. She is also a co-founder at Lester Smith Medical Research Institute. Her A3Cell consultancyhelps practitioners and biotech entrepreneurs navigate the regulatory pathway, as well as design and manage clinical studies. Barbara has worked tirelessly throughout her 25+ year career to engage with university and industry leaders to help bring novel technologies to market and regenerative medicine safely to patients. Her diverse educational background includes physics and computer science at the University of Florida, biomedical engineering graduate studiesat Virginia Tech, a PhD in behavioral psychology, a Doctorate in integrative medicine, numerous medical and data science courses online via major universities and at conferences throughout the world, and Stem Cell Fellowships at both A4M and UCLA. She is a board-certified Diplomat and Fellow of the AABRM.She is an adjunct professor at the Universite Paris Descartes.

Neil Riordan

Founder and Chairman
Medistem Panama, Inc.
Technology Park of the prestigious City of Knowledge in Panama City, Panama

Neil H Riordan is a scientist and developer of regenerative medicine therapeutics, with over 70 peer-reviewed publications and over 40 patents and patent applications. He is the author of Stem Cell Therapy: A Rising Tide, a bestseller featuring accessible information about the scientific concepts driving stem cell therapy, and of MSC: Clinical Evidence Leading Medicine’s Next Frontier, a compilation of stem cell studies with over 800 references to peer-reviewed articles.

Ramon Coronado

Executive Director
Lester Smith Medical Research Institute

Dr. Ramon Coronado, moved from Caracas, Venezuela to San Antonio, Texas in 2009 after completing his B.S. in Polymer Engineering. He studied biomedical engineering through the joint program at UTSA/UTHSCSA and a collaborative effort with the US Army Institute of Surgical Research, receiving his masters in 2012 and his Ph.D. in 2016. Passionate about translating care, he founded Mobile Stem Care in 2013, a company focused on delivering stem cell treatments to animals. Following his success in animal care, Dr. Coronado was named Director for the Lester Smith Medical Research Institute in 2015 where he leads research on a variety of human based cellular therapeutics. He received the CellTex Young Investigator Award in 2016 for his work as Director and continues to explore the boundaries of human cellular therapies. In his free time Dr. Coronado enjoys rock climbing and freediving.

Bruno Peault

Professor
University of California at Los Angeles
Professor and Chair, University of Edinburgh, UK

Dr. Bruno Peault trained with Nicole LeDouarin in Paris and received his PhD in 1987. His research focused on the ontogeny of the blood and vascular systems. He then joined Irving Weissman laboratory at Stanford University. In 1989 he was recruited bySystemix Inc., a biotechnology startup company co-founded by Weissman where he directly contributed to the identification and purification of human hematopoietic stem cells. Bruno Peault was promoted to Research Director at the Centre National de la Recherche Scientifique and established an independent laboratory at the Embryology Institute in Paris in 1992. Bruno Peaultcontinued investigations in human blood stem cells, notably mapping their very origin in a territory adjacent to the embryonic aorta. His group also identified, purified and characterized epithelial stem cells in human upper airways. Bruno Peault was called in 1999 to launch the Institut National de la Sante et de la Recherche Medicale (the French equivalent of NIH) a department studying hematopoietic, endothelial and liver stem cells. His team notably demonstrated that a class of hemogenic endothelial cells is at the origin of emerging human hematopoietic stem cells. In 2003 he moved to the Children’s Hospital and McGowan Institute for Regenerative Medicine in Pittsburgh where, as co-director of the Stem Cell Research Center, he led the prospective identification and purification of two novel categories of human multi-lineage stem cells, muscle myo-endothelial cells and pericytes. This work led to the demonstration that perivascular ancestor cells are at the origin of the elusive mesenchymal stem cells (MSC). He was recruited in 2008 as a Professor at the University of California at Los Angeles, and in 2010 as Professor and Chair at the University of Edinburgh, UK. He currently holds both appointments and leads a collaborative program between both universities.

Jennie Sandqvist

Founder and CEO of the Mih Clinic in Stockholm

Dr. Jennie Sandqvistis a Board certified Chief of Neurology and doctor of functional medicine based in Stockholm, Sweden, with 15 years of clinical experience working with patients.
She specialized in Neurology at the eminent Karolinska University Hospital in Stockholm, where she in addition to her residency, taught both hospital staff and medical students. She is the author of multiple meeting abstracts on a range of topics that include muscular diseases, brain tumors, epilepsy, stroke, multiple sclerosis, degenerative neurological diseases, ALS, intervention treatments, acute neurology and spinal cord injuries.

Marta Garcia

Raj Sisodia

FW Olin Distinguished Professor of Global Business and Whole Foods Market Research Scholar in Conscious Capitalism at Babson College
Co-Founder and Chairman Emeritus of Conscious Capitalism Inc.

Raj was born in India and spent parts of his childhood in Barbados, California and Canada. He was educated as an electrical engineer from the Birla Institute of Technology and Science (BITS, Pilani). He pursued an MBA in Marketing from the Jamnalal Bajaj Institute of Management Studies in Mumbai after which he earned a Ph.D. in Marketing and Business Policy from Columbia University.

Until 1998, he was the Director of Executive Programs and Associate Professor of Marketing at George Mason University in Fairfax, Virginia. From 1985 to 1988, he was Assistant Professor of Marketing at Boston University.

 

Ralph Rogers

CEO
Ralph Rogers Medical Group

Dr. Ralph Rogers is a highly educated and experienced Consultant in regenerative orthopedics who uses innovative regenerative medicine treatments to effectively tackle chronic pain and acute discomfort.
Dr Rogers works to the very highest standards of care and understands the need for speed, precision and quality for all his patients. He provides his patients with cutting-edge non-surgical regenerative treatment options to help improve mobility and reduce pain. These include Lipogems, Platelet Rich Plasma (PRP) injections, Alpha-2 Macroglobulin (A2M) and Extracorporeal Shockwave Therapy (ESWT).